Prediction: TCU 38, Texas Tech 31, Second-Best: Virginia (3-2) at Louisville (3-2), 3 p.m. ET, ESPN) Florida . And after the Tigers fall to 3-3 with a loss to Kentucky, head coach Ed Orgeron's hot-seat meter is going to get cranked up from "mildly toasty" to "raging inferno. Head coach Mike Norvell and the Seminoles headed into the 2022 season with their backs against the wall. Arizona is 3-5 with three straight losses. They won't all be this easy for SDSU, but its first Mountain West Conference win of the season will be a blowout. No. But through five weeks of the season, this matchup has lost a lot of its luster. The Tar Heels are steamrolling through the ACC, with four straight conference wins. Prediction:Arizona State 35, Stanford 17, No. ", No. Georgia will take down the Volunteers to give them their first loss since last season. Given how great both of these defenses have beenonly Georgia (4.6 points allowed per game) has a better scoring defense than Iowa (11.6) and Penn State (12.0)a similar result seems likely. After an exciting opening weekend of college football, we have an idea of who the elite contenders are for the 2022 season. The latest in the sports world, emailed daily. ET, CBS), No. No. I don't expect this game to be that close, but I do think there will be talk of hangovers in the first half of this Friday night game. And back in 2008, the unranked Hawkeyes upset No. LSU needs Jaylon Daniels to play his best game of the season to keep pace with a Tennessee offense that averages 559.3 total yards and 48.5 points per game. 2 Georgia vs. No. Enjoy the free college football picks against the spread as well! That includes impressive victories over Arizona State and Utah, as well as considerably less impressive wins over Arizona and South Florida. No. ET: UTEP 27, Rice 23, Appalachian State at Coastal Carolina, 7:30 p.m. The Buffaloes average 16.3 points, and that won't be nearly enough to keep up with a high-scoring Ducks offense. Oklahoma's Dillon Gabriel left last week's TCU game with a head injury. These are two programs on completely opposite paths. Awesome if you enjoy low-scoring, late drama, that is. James Madison at Arkansas State, 7 p.m. ET: Fresno State 28, Hawai'i 14. ET. Predictions for each Week 6 game are broken into three sections: Top 25 teams, best games between unranked teams and the rest of the slate. It's a bit surprising, given this Sparty team won the Peach Bowl last season. USC at UCLA pick: The computer favors Southern Cal by a 60.5 percent margin over the rival Bruins to stay in the Pac-12 title hunt, but watch . Subscribe to 247Sports YouTube for the latest college football, basketball and recruiting news including live college commitments. It looks like Ducks quarterback Bo Nix is feeling comfortable in Dan Lanning's offense. Prediction: Illinois 24, Michigan State 16. The major factor for this matchup is the Bulldogs defense giving Georgia the better overall talent edge, since Tennessee has had trouble against the pass this season. 3 Ohio State (-25.5) at Michigan State (4 p.m. Quarterback Quinn Ewers had a frightful performance against the Cowboys, but Texas had a chance to regroup. Prediction: Kentucky 45, South Carolina 17. Tar Heels quarterback and true freshman Drake Maye has been sensational this season. The 2021 college football season is underway. Memphis may be able to go shot-for-shot with UCF's offense, but the Knights are only allowing 17.6 points per game, while the Tigers have given up an average of 31.1 points. Michigan has a new look and confidence to them behind quarterback J.J. McCarthy. Both of these teams are trending in opposite directions. Luckily for Georgia, the Dawgs play at home against an Auburn team that is struggling. Oregon has rattled off three straight wins over BYU, Washington State and Stanford. Gambling problem? 13 Arkansas (4-1) at No. Kansas State is fresh off a 48-0 win against the Cowboys, but they weren't at full strength. LSU could put up a fight for a half, but the Tigers seem to be a year or two away from competing in games with Top 10 teams under Kelly. ET: Tulane 30, ECU 27, Tulsa at Navy, 3:30 p.m. 25 LSU (noon ET, ESPN), No. If Key keeps winning, he could win the permanent head coaching job. The TCU Horned Frogs and Kansas Jayhawks are a combined 9-0 going into their showdown in Lawrence, Kansas on Saturday. Prediction: Mississippi State 28, Arkansas 17. But Arkansas had two long passing touchdowns en route to 448 total yards in Week 4 and Mississippi State threw for more than 400 yards this past weekend. 17 TCU (-6.5) at No. The Bearcats aren't making noise as a playoff contender this season, thanks to their loss to Arkansas in Week 1. There's trap games every week and Tulane is going to get caught in one this weekend. 11 Michigan State (5-0) at Rutgers (3-2), Noon ET. But Penn State has yet to cough up the ball more than once in a game and has an impressive plus-six mark of its own. Iowa at No. It was incredibly cool to see Key, who played at Georgia Tech from 1997 to 2000, get an upset victory in his first game as interim head coach. ET. QB Jaxson Dart has thrown for 910 yards and five touchdowns on the year. 20 UCLA, and Stanford certainly shook up the rankings with its 31-24 victory over then-No. Unless otherwise noted, games are assumed to take place on Saturday. Even if the Chants decide to be nice and focus primarily on running the ball (and the clock), you're still talking about an offense that averages 6.4 yards per carry against a defense that just allowed 503 rushing yards in a 59-33 loss to Georgia Southern. Ronald Martinez/Getty Images, Bijan Robinson. No. He doesn't put up fancy numbers or many Heisman-level performances, but the Wolverines live through their success on the ground, and a team like Rutgers won't have an answer for that. NC State fell 30-20 to Clemson last week, and Florida State suffered its first loss to Wake Forest last week. 1 Georgia facing off against No. Mike Norvell looks like he finally has this FSU offense figured out, and quarterback Jordan Travis looks strong so far this season. That duo has rushed for a combined 461 yards and six touchdowns over the last two games, resulting in a win over the Flames and a last-second loss to the Seminoles. The Crimson Tide know that it's time to hit the gas if they want to be playing for the national championship. *Can Florida State's offensive line hold up? 8 Tennessee, Noon ETSee No. This would've been a very exciting matchup with a healthy Devin Leary, who's out for the year with a torn pec. Top 25 rankings, odds, key match . Michigan has impressed the last two weeks, defeating Maryland and beating Iowa on the road handily 27-14. This just seems like a trap game for the Wildcats. Last year, Oklahoma came from behind from a 28-7 first-quarter deficit to win 55-48 in a thriller. In fact, the Hogs' last four opponents have been held without a single passing touchdown and limited to 105.5 passing yards on average. Cincy's offense, which ranks 18th nationally in scoring (40.2 ppg), should have no problems against a USF defense that is tied at 122nd in scoring defense. College Football HQ pick: Oklahoma State wins, 34-28. He's thrown for 1,135 yards and 10 touchdowns on the season, but he threw his third interception of the year against Clemson last week. TCU aided in that process by obliterating the Sooners in Week 5. They gave up 322 rushing yards in the loss to Oregon State two weeks ago, and Utah has averaged better than 6.0 yards per carry in three of its four games. The Boilermakers lost two of their first three games of the season against Penn State and Syracuse, but the win over Minnesota brought them to 3-2. At the beginning of the season, this one looked like it could have major playoff implications. The Black Knights are 1-3, with their only win coming in Week 3 over FCS squad Villanova. 23 Liberty at Arkansas, 4 p.m. This should be another classic in-state rivalry that gives FSU its second straight head-to-head win against the Canes. They'll be back next Friday for a home game against 1-4 California, which should be an easy victory. ET, ESPN3), No. But if that's the case, advantage Virginia Tech, which has the more mobile of the two quarterbacks. The LSU Tigers snuck into the AP Top 25 to be ranked for the first time under Brian Kelly. Payback time for the Buckeyes, who lost a 55-24 game to the Hawks back in 2017 as a CFP contender . ET: Central Michigan 28, Ball State 6, Toledo at Northern Illinois, 3:30 p.m. California started the season with some solid showings, but now it is riding a four-game losing streak, all of which came against Pac-12 opponents. Utah -3 (-110) 1-unit. ET, SEC Network), No. This game is a Premium Pick. ET: South Carolina 34, Vanderbilt 23, JMU at Louisville, 7:30 p.m. ET: Southern Miss 27, Georgia State 14, Middle Tennessee at Louisiana Tech, 3 p.m. At this point, the question isn't: "Will there be upsets? 17 North Carolina at Virginia, Noon ET. Georgia survived a scare last week against an unranked, 2-2 Missouri team. They'll have this week off to prepare for back-to-back road games against Boston College and Miami. Oklahoma State is still figuring things out on offense, averaging a modest (certainly by head coach Mike Gundy's standards) 25.4 points per game. The Bulldogs lost 31-16 to LSU in Week 3, so this game doesn't have a ton of SEC West implications, with Alabama leading the pack. No. Georgia Tech made coaching carousel news last week with the announcement that head coach Geoff Collins and athletic director Todd Stansbury were fired. 13 Arkansas vs. No. It looks like Chip Kelly finally has things rolling at UCLA, as the Bruins are off to their best start since his debut season in 2018. Eligibility restrictions apply. The Utes are still in the hunt for the top spot in the Pac-12 rankings, currently trailing USC, Oregon and UCLA. Oklahoma State is one of the four aforementioned undefeated Big 12 teams. There are three matchups this weekend pitting top 25 ranked teams on . The Lobos have also averaged just 212 yards of total offense and 7.7 points during their current three-game losing streak, so this one should be over by halftime. However, Lance Leipold's Jayhawks will need to play better than they did the Week 5 win over Iowa State to stay atop the Big 12 standings after this weekend. ET. Ole Miss should have no problems winning this one, even on the road. I think this Yellow Jacket team can rally behind him and give him his second win, this time at home. Two years before that, No. The Midshipmen have averaged 45.8 points against the Mustangs, and they enter this contest right after a 34-30 win over UCF in which they rushed for 348 yards and three touchdowns. And if they continue trying to run through a brick wall this coming weekend against Kentucky's defense, they're only going to hurt themselves. But that ship sailed last Saturday, so Mississippi State might have more motivation entering this one. Oklahoma State is a 9-point favorite. NC State is just a 3.5-point favorite at home, but it'll be interesting to see how this Wolfpack team rebounds from the home loss to Clemson. The Tigers were No. ET (Thursday). That could make all the difference in covering the 6.5 points if they do not come out on top. UCF may be on the road, but a game at Memphis never hurt anybody. ET. 3 Penn State 24-23 on a last-second field goal. But other than their battle against Wake Forest, Liberty has played a weak schedule. Since joining the AAC, SMU has had quite a bit of documented trouble with Navy's triple-option offense. ET: Coastal Carolina at UL Monroe, 8 p.m. Saturday's game against Utah will prove if this UCLA team is for real or not. Unless otherwise noted, games are assumed to take place on Saturday. The Razorbacks had a chance to defeat TAMU, but doinked a game-winning field goal attempt off the top of the upright. Unfortunately, quarterback Spencer Sanders has been digressing each week throughout the season so far. Truly, it wouldn't be a surprise if Coastal Carolina scores on every possession. Kansas' Jalon Daniels has thrown for 983 yards, 11 touchdowns and just one interception. We were guaranteed at least four losses because of that many meetings between ranked teams, but No. 6 Oklahoma (5-0), Noon ET (in Dallas), No. It's just not the best matchup on the schedule. Bleacher Report's Top plays of the 2020 college football season. Both SEC West contenders are in desperate need of a bounce-back game if they want to remain in the hunt for a division crown. Odds and lines subject to change. However, Iowa has done such an incredible job of both forcing turnovers and converting short-field drives into points that a big interception or two almost feels inevitable. ET: Virginia's Brennan Armstrong is averaging nearly 400 passing yards per game, but Louisville's Malik Cunningham is the quarterback to watch in this one. 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