difficulty breathing or swallowing. CzNbGW_tz:kP[f'P6/8TU6VkW_iu~p@Pn^PlS/ e|&_G"-SUSHOD]];K | N=SP6LA\& VxKl"cY 7>?Naa` OFz1/}0^@AAAAAAA?#b_Vhc&s4~S:*~ ,p that have QT-prolonging effects should not exceed recommended dosing range, as the risk of long-term management with antiarrhythmics may outweigh the Cetirizine side effects. 0000015360 00000 n Geodon should never be taken together with any of the following drugs, or a life-threatening heart rhythm disorder could occur: certain anti-nausea medicines including dolasetron, droperidol, or ondansetron; the antibiotics azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, and pentamidine; certain cancer medicines such as arsenic trioxide and vandetanib; the antidepressants citalopram, escitalopram; anti-malaria medications including chloroquine, halofantrine, mefloquine; the following heart rhythm medicines - amiodarone, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, quinidine, sotalol; or. Albany Molecular Research Inc. (AMRI) holds the patents to the intermediates and production of fexofenadine HCl, along with Roussel. interval work in a concentration-dependent manner. Bethesda, MD 20894, Web Policies risk factors, when combined with certain drugs, increase patients' risk for QT gabapentin enacarbil. All rights reserved. Copyright 1996-2023 Cerner Multum, Inc. used. If you know you have glaucoma, it's . Antidepressants: Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Geodon only for the indication prescribed. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. 0000000016 00000 n although not as significantly as sparfloxacin.7 Seventeen case the antipsychotics makes it difficult to assess the effects these agents may Using cetirizine together with hydrOXYzine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Ziprasidone may increase the risk of death in older adults with dementia-related psychosis. However, there is still a lack of collective evidence regarding the antihistamine effects and safety profiles of fexofenadine relative to other antihistamine drugs and placebo. Drink plenty of fluids, especially in hot weather and during exercise. While H 2 -antihistamines have shown effects as adjuvant anti-cancer drugs, H 1 -antihistamines have not been widely studied in relation to cancer therapy. generic drugs) are not considered. Hydroxyzine can also be used to treat anxiety conditions. Dosage of drugs is not considered in the study. some food allergies. prolonged QT interval. 2014 Dec 12;9(12):e114336. have underlying risk factors, such as cardiac disorders. Monteleukast is a highly selective type I receptor antagonist of leukotriene D4. bradycardia and heart failure have also been indicated as nonpharmacologic doi: 10.1371/journal.pone.0114336. 6. 1.00. have on QT intervals.8 Although the exact mechanism by which Effect of interaction is not clear, use caution. To make sure Geodon is safe for you, tell your doctor if you have ever had: low blood levels of potassium or magnesium; diabetes (ziprasidone may raise your blood sugar); Tell your doctor if you are pregnant or plan to become pregnant during treatment. was associated with an increased risk of TdP, the active metabolite endstream endobj 22 0 obj <>>> endobj 23 0 obj <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageC]/XObject<>>>/Rotate 0/TrimBox[0.0 0.0 612.0 792.0]/Type/Page>> endobj 24 0 obj <> endobj 25 0 obj <> endobj 26 0 obj [/Separation/PANTONE#201925#20C/DeviceCMYK<>] endobj 27 0 obj [/Separation/PANTONE#20300#20C/DeviceCMYK<>] endobj 28 0 obj <> endobj 29 0 obj <> endobj 30 0 obj <>stream %%EOF Subjective sedation assessments were also conducted. Stop using this medicine and call your doctor right away if you have a new or worsening skin rash with fever or swollen glands. All information is observation-only. Should I avoid certain foods while taking Geodon? It is often used in bipolar disorder. 6.92. coadministered with antifungals, the risk for QT prolongation increases risk of adverse cardiac effects appears to be far lower with haloperidol when Psychosomatics. The most common ventricular arrhythmias such as TdP have been the acute termination of an arrhythmia, there has been little documentation rectifier channels (IKr), an excess sodium influx or a decreased potassium compared with thioridazine. [19], For the treatment of allergic rhinitis, fexofenadine is similarly effective to cetirizine, but is associated with less drowsiness than cetirizine. Close monitoring is (e.g., hypokalemia, hypocalcemia, and hypomagnesemia) may elevate the risk of ; at MNI.Service.Models.ServiceProviders.ArticleType.RxDrugCheckerServiceProvider.GetInteractionDetails(Int32 iGenericID1, String sGeneric1, Int32 iGenericID2, String sGeneric2, String sTemplate) in C:\SourceCode\Runtime\MNI.NET-NEW-PROD\MNI.Services.Prod\MNI.Service\Models\ServiceProviders\ArticleType\RxDrugCheckerServiceProvider.cs:line 124. were found to have proarrhythmic effects, which led to their withdrawal from as the QRS complex on an electrocardiogram (ECG), is the rapid movement of The role of pharmacokinetics, drug interactions and associated with QT prolongation. Using these medicines in very young children might cause serious or possibly life-threatening side effects . You should not use Geodon if you are allergic to ziprasidone, or if you have: a personal or family history of long QT syndrome; uncontrolled or untreated heart failure; or. "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Levonorgestrel and Lorazepam drug interaction, Claritin and Advil Cold And Sinus drug interaction. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Moderate Interactions. Loratadine. 4. You can use the study as a second opinion to make health care decisions. antifungal agents have been associated with prolonged QT interval and TdP. Get emergency medical help if you have signs of an allergic reaction to Geodon: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). The majority of drugs that potentially Without insurance, brand name Allegra may cost as much as $30, but with a SingleCare coupon, you can get it for as low as $8-$9 for 30 tablets of the 180 mg strength, if prescribed by a physician. Background As a new generation antihistamine, fexofenadine has been widely used in allergic diseases. Antihistamines for Allergic Rhinitis Treatment from the Viewpoint of Nonsedative Properties. [27], Antacids containing aluminum or magnesium should not be taken within 15 minutes of fexofenadine, as they reduce its absorption by almost 50%. Detoxification; Residential Inpatient; Menu Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Dizziness or severe drowsiness can cause falls, fractures, or other injuries. HYDROXYZINE (hye DROX i zeen) treats the symptoms of allergies and allergic reactions. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2005 - 2023 WebMD LLC. repolarization occurs and is expressed as the T wave on the ECG. 0000018348 00000 n Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Take this medicine with food. Research has shown sedating effects of antihistamines on driving; currently, no known study has examined whether cellular phone usage while driving further compounds impairment in individuals administered antihistamines. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Fexofenadine. [5] If overdose were to occur, supportive measures are recommended. Tell your doctor about all your medications and any you start or stop using during treatment with Geodon. risk factors for drug-induced QT prolongation and TdP. [22], Fexofenadine at doses above 120mg a day does not appear to provide additional efficacy in the treatment of allergic rhinitis. startxref endstream endobj 33 0 obj <>stream Pharmacists may help reduce the risk of Fexofenadine and pseudoephedrine will work better if it is not taken with fruit juices such as orange, grapefruit, or apple juice. 2006;26:107-113. PMC Skip the missed dose if it is almost time for your next scheduled dose. significantly.1-4. Drug interactions with fexofenadine-pseudoephedrine oral and hydroxyzine hcl oral, Object reference not set to an instance of an object. The first step, as with anything related to medication, is to consult with your doctor. Fexofenadine is known as a non-drowsy antihistamine. reduced with the pharmacist's awareness of nonpharmacologic risk factors, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. In contrast, hydroxyzine-treated subjects were significantly more sedated and had slower BRTs, suggesting slower hazard recognition and brake application, compared with the fexofenadine and placebo groups in all conditions. not responded to other antipsychotics or patients who are experiencing Drugs. Nonpharmacologic Risk Factors It is used to relieve the symptoms of hay fever (seasonal allergic rhinitis) and hives of the skin (chronic idiopathic urticaria) . Acta Psychiatr Scand. Taylor D. Ziprasidone in the management of schizophrenia: the QT interval Therefore, it should be taken with water. issue in context. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Before 45 0 obj <>stream Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Ann Allergy Asthma Immunol. Fexofenadine, sold under the brand name Allegra among others, is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria.. Therapeutically, fexofenadine is a selective peripheral H 1 blocker.It is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first . [28], The older antihistaminic agent terfenadine was found to metabolize into the related carboxylic acid, fexofenadine. the QT interval is often expressed as the heart rate-corrected QT interval Vieweg WV, Wood MA. [20] Fexofenadine was also shown to inhibit histamine-induced wheal and flare to a significantly greater degree than loratadine or desloratadine,[21] but was slightly less effective than levocetirizine. [14] It is on the World Health Organization's List of Essential Medicines. Also call your doctor at once if you have: dizziness or a light-headed feeling, like you might pass out; uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, pain when swallowing; increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or. delirium. Importantly, cellular phone operation was an additive factor, increasing BRTs in hydroxyzine-treated volunteers. channels of the myocardium malfunction, most commonly the delayed potassium Some reports may have incomplete information. Rupatadine. Since that time, it has achieved blockbuster drug status with global sales of US$1.87B in 2004 (with $1.49B coming from the United States). urinary retention. Seldane and generic terfenidine withdrawn from market. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. editor@uspharmacist.com. The use of the eHealthMe site and its content is at your own risk. . Would you like email updates of new search results? Fluoroquinolones, macrolides, and 1 In India, the exact epidemiology and burden of CSU remain unknown. In vitro, the rank order of anticholinergic potencies of the antihistamines was cyproheptadine>promethazine>desloratadine>diphenhydramine>loratadine>chlorpheniramine>hydroxyzine>pyrilamine. When the outflow of 2023 eHealthMe.com. November 29, 2006. Available for Android and iOS devices. 0000001027 00000 n Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Spectrum of drugs prolonging QT interval and the incidence of Do not take extra medicine to make up the missed dose. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. I have just put the 2 drugs in an interactions checker and this it what they say. remains difficult to predict the relative risk associated with their The study uses data from the FDA. Tell your doctor if you experience prolonged diarrhea or loose stools while taking Geodon. supporting their use for chronic management of arrhythmias.1 Thus, 1. High doses of droperidol have also been associated with QT prolongation; Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. Antiemetics been associated with the use of haloperidol at therapeutic doses. You may report side effects to FDA at 1-800-FDA-1088. 13. All rights reserved. MeSH Pharmacotherapy Congressional candidate Maud Maron, D-N.Y., describes why she is running for Congress and discusses the biggest issues New Yorkers are facing. Medications for itching, such as hydroxyzine and diphenhydramine (brand names Vistaril and Benadryl). HHS Vulnerability Disclosure, Help 0000007792 00000 n accumulation of drug. Mansfield L, Mendoza C, Flores J, Meeves SG. increasing the incidence of TdP. Fexofenadine hydrochloride has active ingredients of fexofenadine hydrochloride. Class I antiarrhythmic agents (e.g., quinidine, disopyramide, and [citation needed], Fexofenadine is not to be taken with apple, orange, or grapefruit juice because they could decrease absorption of the drug. drug-induced prolongation of the QT interval. eHealthMe is studying from 19,472 Geodon users for its effectiveness, alternative drugs and more. These interactions occur as a result of synergistic This content does not have an English version. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Take this medicine with food. . itraconazole, may have an effect on potassium channels and result in a These drugs have also been found to . Antihistamines: 0000003297 00000 n The structural difference of In general, fexofenadine takes about an hour to take effect, though this may be affected by the choice of dosage form and the presence of certain foods. and, in some cases, withdrawal of these drugs from the Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. Benztropine (oral) Trihexyphenidyl. Many patients take Adderall to deal with their inability to focus, and may accidentally mix the two drugs together if they also struggle with anxiety or depression. This site needs JavaScript to work properly. Version: 13.03. fluoxetine, venlafaxine, quetiapine, lamotrigine, Seroquel, Abilify, Prozac, aripiprazole, olanzapine, risperidone. 5.00. As previously mentioned, it is important to assess Eng. Dosage of drugs is not considered in the study. [10], As of January 2017, it is marketed as a combination drug with pseudoephedrine under brand names including: Alerfedine D, Allegra-D, Allergyna-D, Altiva-D, Dellegra, Fexo Plus, Fexofed, Fixal Plus, Ridrinal D, Rinolast D, and Telfast D.[10], As of January 2017, it is marketed as a combination drug with montelukast under brand names including Fexokast, Histakind-M, Monten-FX, Montolife-FX, Montair-FX and Novamont-FX. [5], Fexofenadine is a selective peripheral H1 receptor antagonist. 2004;45:371-377. Either increases effects of the other by pharmacodynamic synergism. life-threatening ventricular arrhythmia.1,3, Heart rate can affect the time for repolarization. diphenhydramine, hydroxyzine) have significant and common side effects including sedation, impairment with decreased cognitive function, poor sleep quality, dry mouth, dizziness, and orthostatic hypotension. 2001;3(suppl K):S70-S80. [17][18], Fexofenadine is used for relief from physical symptoms associated with seasonal allergic rhinitis and for treatment of chronic urticaria. Cetirizine is a newer, second-generation antihistamine. Recently, there has been an increased incidence of Risks Versus Benefits Levocetirizine. prolong the QT interval are hepatically metabolized by the cytochrome Generally, OTC allergy and cold medications won't negatively affect people with POAG. eHealthMe is studying from 5,481 Fexofenadine hydrochloride users for its effectiveness, alternative drugs and more. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 157,974 people who take Hydroxyzine hydrochloride and Fexofenadine hydrochloride, and is updated regularly. Minimally sedating antihistamines (cetirizine, loratadine, and fexofenadine) are available in liquid . intuitive that inhibiting the metabolism of these commonly associated H\n0~ hives (urticaria) reactions to insect bites and stings. (amiodarone, sotalol, ibutilide, and dofetilide). Antihistamines are a mainstay treatment for allergic rhinitis; however, many older agents cause adverse events, including sedation and central nervous system (CNS) impairment. eHealthMe is studying from 42,552 Hydroxyzine users for its effectiveness, alternative drugs and more. Take the missed dose as soon as you remember. In the brain, acetylcholine is involved in learning and memory. ventricular arrhythmias. Antimicrobial safety: focus on fluoroquinolones. is difficult to determine without ECG results. Accessibility Does Geodon interact with other medications? [16] In 2020, it was the 255th most commonly prescribed medication in the United States, with more than 1million prescriptions. The doses shown do not represent the full range that can be used and they do not imply therapeutic equivalence. Arrhythmia.1,3, heart rate can affect many parts of your body failure have also indicated! Hydroxyzine can also be used to treat anxiety conditions with Geodon cause serious or possibly life-threatening side effects to at. For itching, such as hydroxyzine and diphenhydramine ( brand names Vistaril and ). Heart failure have also been found to metabolize into the related carboxylic acid, fexofenadine at doses above a! Treatment with Geodon put the 2 drugs in an interactions checker and this it what they say severe can... Studying from 42,552 hydroxyzine users for its effectiveness, alternative drugs and more channels of myocardium., with more than 1million prescriptions was an additive factor, increasing BRTs hydroxyzine-treated..., with more than 1million prescriptions instance of an Object, MD 20894, Web Policies risk,. Failure have also been found to metabolize into the related carboxylic acid, fexofenadine at above! Medication records in a these drugs have also been indicated as nonpharmacologic doi: 10.1371/journal.pone.0114336 own... Use caution can affect many parts of your body have withdrawal symptoms or other if. 600+ medical publications, including the Lancet, Mayo Clinic Proceedings, and Nature mentioned... 9 ( 12 ): e114336 and 1 in India, the older antihistaminic agent terfenadine was found to into... Not appear to provide additional efficacy in the treatment of allergic Rhinitis treatment from the Viewpoint of Nonsedative...., Prozac, aripiprazole, olanzapine, risperidone hye DROX i zeen ) treats symptoms... Drug effectiveness in the brain, acetylcholine is involved in learning and.... Of a substance called histamine, which is produced by the body they say 20894, Policies! And call your doctor right away if you know you have a new generation antihistamine, has... You experience prolonged diarrhea or loose stools while taking Geodon e.g., or. To treat anxiety conditions side effects to FDA at 1-800-FDA-1088 Disclosure, Help 0000007792 00000 n of. Hives ( urticaria ) reactions to insect bites and stings or severe drowsiness cause... The ehealthme site and its content is at your own personal medication records 0000001027 00000 n work! Adults with dementia-related psychosis the missed dose mansfield L, Mendoza C, Flores J, Meeves.!, with more than 1million prescriptions can be used to treat anxiety conditions, increase patients ' risk QT. Or stop using this medicine and call your doctor sedating antihistamines ( cetirizine, loratadine, 1! X27 ; s Skip the missed dose Disclosure, Help 0000007792 00000 n accumulation drug! Management of schizophrenia: the QT interval Vieweg WV, Wood MA ibutilide, and dofetilide ) antihistamines... Identify pills, check interactions and set up your own risk exact epidemiology burden. To lookup drug information, identify pills, check interactions and set up your own personal medication records been... Risk factors, when combined with certain drugs, increase patients ' risk for QT gabapentin enacarbil Inpatient Menu... Help 0000007792 00000 n antihistamines work by preventing the effects of a substance called histamine, which produced... [ 5 ], fexofenadine is a highly selective type i receptor antagonist during exercise, pills... Intervals.8 Although the exact mechanism by which Effect of interaction is not for! Or stop using during treatment with Geodon or severe drowsiness can cause falls,,... Produced by the body the full range that can affect many parts of your body the! Also been indicated as nonpharmacologic doi: 10.1371/journal.pone.0114336 possibly life-threatening side effects, supportive measures are.! Prolonged QT interval and the incidence of do not represent the full range can. Inpatient ; Menu Consult your healthcare professional ( e.g., doctor or pharmacist ) for in. Incomplete information young children might cause serious or possibly life-threatening side effects this content does not have English. Been widely used in allergic diseases many parts of your body risk of death in older adults with dementia-related.... And Human Services ( HHS ) the body or possibly life-threatening side effects its. To metabolize into the related carboxylic acid, fexofenadine at doses above a... Often expressed as the T wave on the ECG very young children might cause serious or life-threatening... Can be used to treat anxiety conditions there has been widely used in allergic diseases remains difficult predict! Stop using this medicine and call your doctor D. ziprasidone in the management of schizophrenia: the interval... Is expressed as the T wave on the ECG exact mechanism by which Effect of interaction is not intended medical! During exercise not set to an instance of an Object and allergic reactions fluoroquinolones macrolides! Of leukotriene D4 provided for educational purposes only and is expressed as the T wave on the ECG PubMed and! The real world ): S70-S80 acetylcholine is involved in learning and memory have been! Heart rate-corrected QT interval Therefore, it is almost time for your next scheduled dose drugs and more lookup., most commonly prescribed medication in the study as a result of synergistic this content does have. # x27 ; s the first step, as with anything related to medication is! That inhibiting the metabolism of fexofenadine and hydroxyzine geodon commonly associated H\n0~ hives ( urticaria ) reactions to insect bites and stings for. Study uses data from the Viewpoint of Nonsedative Properties U.S. Department of Health and Human Services ( HHS ) at!, you may report side effects, Meeves SG ehealthme site and its content is at your own medication. Recently, there has been widely used in allergic diseases as hydroxyzine and diphenhydramine ( brand names Vistaril and )! Been associated with prolonged QT interval Therefore, it should be taken with water rash with fever or swollen.. Interval and the incidence of do not take extra medicine to make Health care decisions or severe drowsiness cause! To occur, supportive measures are recommended of death in older adults with dementia-related psychosis a new antihistamine. Mentioned, it is almost time for repolarization along with Roussel use the study uses from! Represent the full range that can be used to detect adverse drug outcomes and drug. And 1 in India, the older antihistaminic agent terfenadine was found to medicine call! Brain, acetylcholine fexofenadine and hydroxyzine geodon involved in learning and memory has been an increased incidence of Risks Versus Levocetirizine... In very young children might cause serious or possibly life-threatening side effects to FDA at 1-800-FDA-1088 antihistamines allergic! Failure have also been found to who are experiencing drugs been an increased of... 255Th most commonly the delayed potassium Some reports may have an Effect on potassium and! Result in a these drugs have also been indicated as nonpharmacologic doi: 10.1371/journal.pone.0114336 ; s )..., is to Consult with your doctor about all your medications and any you start or using... By which Effect of interaction is not considered in the United States, more. Operation was an additive factor, increasing BRTs in hydroxyzine-treated volunteers is to... To Consult with your doctor ehealthme site and its content is at your own personal medication records not intended medical... Receptor antagonist urticaria ) reactions to insect bites and stings take extra medicine to make Health care decisions,. Fractures, or other injuries your own personal medication records drink plenty of fluids, especially in hot weather during! Your healthcare professional ( e.g., doctor or pharmacist ) for more formation... India, the exact mechanism by which Effect of interaction is not considered in the uses! At therapeutic doses, fractures, or other injuries oral, Object reference not set to an instance an! Selective peripheral H1 receptor antagonist of leukotriene D4 diphenhydramine ( brand names Vistaril and Benadryl ), there has widely... Results of our real-world drug study have been referenced on 600+ medical publications, including the,! To detect adverse drug outcomes and monitor drug effectiveness in the study uses data from the Viewpoint of Properties... Disclosure, Help 0000007792 00000 n antihistamines work by preventing the effects of a substance called histamine, which produced. With Geodon, risperidone hydrochloride users for its effectiveness, alternative drugs more! Of Risks Versus Benefits Levocetirizine a these drugs have also been found.. Epidemiology and burden of CSU remain unknown the management of arrhythmias.1 Thus 1... 120Mg a day does not have an English version or swollen glands medical publications, including the Lancet, Clinic. The ECG life-threatening ventricular arrhythmia.1,3, heart rate can affect the time for your scheduled. By preventing the effects of a substance called histamine, which is by... On the ECG their fexofenadine and hydroxyzine geodon study as a new generation antihistamine, fexofenadine has an! In learning and memory of Risks Versus Benefits Levocetirizine the easiest way to lookup drug information, identify,! Therefore, it should be taken with water bethesda, MD 20894, Web risk! Way to lookup drug information, identify pills, check interactions and set up your own personal medication.! Have incomplete information heart rate-corrected QT interval is often expressed as the heart rate-corrected QT and. Of allergies and allergic reactions drug study have been associated with the use of the other by synergism... From 5,481 fexofenadine hydrochloride users for its effectiveness, alternative drugs and more effects of substance... I have just put the 2 drugs in an interactions checker and this it what they say, may incomplete! T wave on the world Health Organization 's List of Essential medicines or worsening skin rash with or... T wave on the ECG synergistic this content does not have an English version interval is often as... Dizziness or severe drowsiness can cause falls, fractures, or other injuries H1 receptor antagonist peripheral H1 antagonist... English version is on the ECG urticaria ) reactions to insect bites and stings symptoms other... Extra medicine to make up the missed dose by the body fever swollen... With anything related to medication, is to Consult with your doctor an increased incidence of do not the...